Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.5K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cochlear clefts in children: prevalence, characteristics, and clinical implications.

Pediatric radiology·2025
Same author

Brain and Spinal Cord MRI Findings in Thai Multiple Sclerosis Patients.

Journal of imaging·2023
Same author

Prevalence of Sclerotic Pterygoid Plate in Pretreatment Nasopharyngeal Carcinoma.

Asian Pacific journal of cancer prevention : APJCP·2022
Same author

Diffusion MRI in Evaluation of Pediatric Posterior Fossa Tumors.

Asian Pacific journal of cancer prevention : APJCP·2021
Same author

Evaluation of Perienhancing Area in Differentiation between Glioblastoma and Solitary Brain Metastasis.

Asian Pacific journal of cancer prevention : APJCP·2020
Same author

Preoperative MRI evaluation of meningioma consistency: A focus on detailed architectures.

Clinical neurology and neurosurgery·2018

Related Experiment Video

Updated: Dec 27, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

23.0K

Grading Gliomas Capability: Comparison between Visual Assessment and Apparent Diffusion Coefficient (ADC) Value

Warinthorn Phuttharak1, Jureerat Thammaroj1, Sakda Wara-Asawapati2

  • 1Department of Radiology,Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Asian Pacific Journal of Cancer Prevention : APJCP
|February 28, 2020
PubMed
Summary
This summary is machine-generated.

Diffusion-weighted imaging (DWI) visual scale and apparent diffusion coefficient (ADC) values can differentiate low- and high-grade gliomas. ADC measurements showed higher accuracy than visual scale assessment for glioma grading.

Keywords:
Diffusion magnetic resonance imagingKey words : GliomaMRI

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.1K
Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

12.1K

Related Experiment Videos

Last Updated: Dec 27, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

23.0K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.1K
Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

12.1K

Area of Science:

  • Neuroimaging
  • Oncology
  • Radiology

Background:

  • Gliomas are primary brain tumors with varying grades of malignancy.
  • Accurate grading of gliomas is crucial for treatment planning and prognosis.
  • Distinguishing between low- and high-grade gliomas can be challenging using conventional MRI sequences.

Purpose of the Study:

  • To compare the diagnostic accuracy of diffusion-weighted imaging (DWI) visual scale assessment versus apparent diffusion coefficient (ADC) value measurement in grading gliomas.
  • To evaluate the effectiveness of these methods in differentiating low-grade from high-grade gliomas.

Main Methods:

  • A retrospective study included 38 patients with pathologically proven gliomas (18 low-grade, 20 high-grade).
  • MRI and biopsy were performed on all patients.
  • Two readers assessed DWI visual scale independently, with disagreements resolved by consensus.
  • One reviewer measured the ADC value of the solid tumor portion.
  • Diagnostic accuracy was compared using receiver operating characteristic (ROC) curve analysis (area under the curve - AUC).

Main Results:

  • Both DWI visual scale and ADC values significantly differentiated low- and high-grade gliomas (P < 0.002 and P < 0.001, respectively).
  • ADC value measurement achieved higher diagnostic accuracy (89.47%) compared to the visual scale (73.68%).
  • The optimal ADC cutoff for differentiating grades was 1119.48 x10^-6 mm²/s, with high sensitivity (90%) and specificity (88.89%).

Conclusions:

  • Both DWI visual scale and ADC value measurements are capable of differentiating between low- and high-grade gliomas.
  • ADC value measurement demonstrated superior diagnostic accuracy for glioma grading compared to the visual scale.
  • Further large-scale prospective studies are recommended to validate these findings.