Related Experiment Video

Updated: Dec 27, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

4.2K

Aortic regurgitation after closure of ventricular septal defect by transcatheter device: the long-term complication

Yuehu Han1, Hongling Li2, Hailong Zhu1

  • 1Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Cardiology in the Young
|February 28, 2020
PubMed

Insights

Transcatheter closure for ventricular septal defects (VSD) is effective short-term, but long-term follow-up reveals increasing aortic regurgitation 9-12 years post-procedure, questioning its lasting success.

Area of Science:

  • Cardiology
  • Medical Devices
  • Congenital Heart Disease

Background:

  • Ventricular septal defect (VSD) is a common congenital heart defect (CHD).
  • Transcatheter VSD closure offers an alternative to surgery with good short- and mid-term outcomes.
  • Long-term data on transcatheter VSD closure efficacy is limited.

Observation:

  • Aortic regurgitation was observed in patients 9-12 years after transcatheter VSD closure.
  • The severity of aortic regurgitation progressively increased over time in these patients.

Findings:

  • Transcatheter VSD closure demonstrates safety and efficacy in the short and mid-term.
  • Long-term follow-up indicates a potential for developing aortic regurgitation years after the procedure.

Implications:

  • The long-term durability of transcatheter VSD closure may be less favorable than previously assumed.
  • Further research is needed to understand and mitigate late-onset aortic regurgitation after transcatheter VSD closure.
  • Clinical practice may need to adapt surveillance protocols for patients undergoing transcatheter VSD closure.

Keywords:
Ventricular septal defectaortic regurgitationfollow-upoccludertranscatheter closure

More Related Videos

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.5K
Closure of a Patent Foramen Ovale PFO: An Intervention Sequence10:52

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence

Published on: December 23, 2022

5.2K

Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
357
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
316
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
193
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
302
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
223
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
308