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Updated: Dec 27, 2025
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
The 2019 novel coronavirus resource
Wen-Ming Zhao1, Shu-Hui Song2, Mei-Li Chen2
1China National Center for Bioinformation & National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Insights
A new resource, 2019 Novel Coronavirus Resource (2019nCoVR), centralizes genomic data and literature for the 2019 novel coronavirus (2019-nCoV). This aids research into virus origins, variation, detection, and treatment.
Area of Science:
- Virology
- Bioinformatics
- Public Health
Background:
- The 2019 novel coronavirus (2019-nCoV) outbreak has caused a global health crisis.
- Rapid data sharing is crucial for understanding and combating the virus.
Purpose of the Study:
- To establish a centralized resource for 2019-nCoV data.
- To facilitate data sharing and accessibility for researchers worldwide.
Main Methods:
- Integrated genomic and proteomic sequences with metadata from multiple public databases.
- Incorporated scientific literature, news, and popular articles.
- Developed visualization tools for genome variation analysis.
Main Results:
- The 2019 Novel Coronavirus Resource (2019nCoVR) was created, providing a comprehensive data repository.
- The resource links to related databases, enabling data submission and sharing.
- It supports studies on virus classification, origin, variation, detection, and therapeutic development.
Conclusions:
- 2019nCoVR serves as a foundational platform for 2019-nCoV research.
- Enhanced data accessibility and sharing accelerate scientific progress against the outbreak.
Abstract:
An ongoing outbreak of a novel coronavirus infection in Wuhan, China since December 2019 has led to 31,516 infected persons and 638 deaths across 25 countries (till 16:00 on February 7, 2020). The virus causing this pneumonia was then named as the 2019 novel coronavirus (2019-nCoV) by the World Health Organization. To promote the data sharing and make all relevant information of 2019-nCoV publicly available, we construct the 2019 Novel Coronavirus Resource (2019nCoVR, https://bigd.big.ac.cn/ncov). 2019nCoVR features comprehensive integration of genomic and proteomic sequences as well as their metadata information from the Global Initiative on Sharing All Influenza Data, National Center for Biotechnology Information, China National GeneBank, National Microbiology Data Center and China National Center for Bioinformation (CNCB)/National Genomics Data Center (NGDC). It also incorporates a wide range of relevant information including scientific literatures, news, and popular articles for science dissemination, and provides visualization functionalities for genome variation analysis results based on all collected 2019-nCoV strains. Moreover, by linking seamlessly with related databases in CNCB/NGDC, 2019nCoVR offers virus data submission and sharing services for raw sequence reads and assembled sequences. In this report, we provide comprehensive descriptions on data deposition, management, release and utility in 2019nCoVR, laying important foundations in aid of studies on virus classification and origin, genome variation and evolution, fast detection, drug development and pneumonia precision prevention and therapy.
