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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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The 2019 novel coronavirus resource.

Wen-Ming Zhao1, Shu-Hui Song2, Mei-Li Chen2

  • 1China National Center for Bioinformation & National Genomics Data Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Yi Chuan = Hereditas
|February 28, 2020
PubMed
Summary

A new resource, 2019 Novel Coronavirus Resource (2019nCoVR), centralizes genomic data and literature for the 2019 novel coronavirus (2019-nCoV). This aids research into virus origins, variation, detection, and treatment.

Keywords:
2019 novel coronavirus2019nCoVRChina National Center for Bioinformation (CNCB)National Genomics Data Center (NGDC)genomic data sharing

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Area of Science:

  • Virology
  • Bioinformatics
  • Public Health

Background:

  • The 2019 novel coronavirus (2019-nCoV) outbreak has caused a global health crisis.
  • Rapid data sharing is crucial for understanding and combating the virus.

Purpose of the Study:

  • To establish a centralized resource for 2019-nCoV data.
  • To facilitate data sharing and accessibility for researchers worldwide.

Main Methods:

  • Integrated genomic and proteomic sequences with metadata from multiple public databases.
  • Incorporated scientific literature, news, and popular articles.
  • Developed visualization tools for genome variation analysis.

Main Results:

  • The 2019 Novel Coronavirus Resource (2019nCoVR) was created, providing a comprehensive data repository.
  • The resource links to related databases, enabling data submission and sharing.
  • It supports studies on virus classification, origin, variation, detection, and therapeutic development.

Conclusions:

  • 2019nCoVR serves as a foundational platform for 2019-nCoV research.
  • Enhanced data accessibility and sharing accelerate scientific progress against the outbreak.