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Prolonged elevation of plasma HMGB1 is associated with cognitive impairment in intensive care unit survivors

Emily Brück1,2, Julie Lasselin3,4,

  • 1Department of Physiology and Pharmacology, Karolinska Institute, 171 77, Stockholm, Sweden.

Intensive Care Medicine
|February 28, 2020
PubMed
Abstract

No abstract available in PubMed .

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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