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Ewing sarcoma in an infant and review of the literature
Çağlayan Selenge Bedük-Esen1, Melis Gültekin1, G Burça Aydın2
1Departments of Radiation Oncology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Insights
Ewing sarcoma (ES) is rare in infants, and treatment lacks standard guidelines. This case highlights a rapidly fatal outcome in a 7-month-old despite aggressive chemotherapy and radiotherapy for mastoid bone ES with metastases.
Area of Science:
- Pediatric Oncology
- Skeletal System Tumors
Background:
- Ewing sarcoma (ES) is a rare pediatric malignancy with a controversial prognosis in infants.
- Standard treatment protocols for infants with ES are lacking, particularly regarding radiotherapy due to potential late side effects.
Abstract:
Bedük Esen ÇS, Gültekin M, Aydın GB, Akyüz C, Karlı Oğuz K, Orhan D, Cengiz M, Gürkaynak M, Yıldız F. Ewing sarcoma in an infant and review of the literature. Turk J Pediatr 2019; 61: 760-764. Ewing sarcoma (ES) is a rare tumor in infants and prognosis is controversial. There are no standard recommendations for treatment in such very young patients. Generally, radiotherapy (RT) is not a part of treatment in infants due to the risk of severe late side effects. In this case report, we report a 7-month-old boy with diagnosis of left mastoid bone ES with lung metastases at diagnosis, showing a rapidly fatal outcome despite aggressive systemic chemotherapy and RT without surgery.
