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Related Experiment Videos

A new portacaval shunt.

J T Kissinger1, H E Griffin, S A Campbell

  • 1Department of Laboratory Animal Science, Smith Kline and French Laboratories, King of Prussia, Pennsylvania 19406-0939.

Journal of Pharmacological Methods
|December 1, 1988
PubMed
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A novel prosthetic portacaval shunt was developed and tested. This new shunt is easily implanted, reduces surgery time, and shows no signs of thrombosis or venous stasis.

Area of Science:

  • Biomedical Engineering
  • Vascular Surgery
  • Prosthetic Devices

Background:

  • Portacaval shunts are used in surgical procedures.
  • Existing methods may require anticoagulants and longer operative times.
  • Development of improved prosthetic devices is ongoing.

Purpose of the Study:

  • To construct and evaluate a new prosthetic, segmented polyether polyurethane portacaval shunt.
  • To assess the shunt's performance in a short-term pharmacokinetic study.
  • To determine if the new shunt reduces operative time and complications.

Main Methods:

  • Construction of a segmented polyether polyurethane portacaval shunt with quick-connect anastomotic ends.
  • Surgical implantation of the shunt in a study cohort.

Related Experiment Videos

  • Evaluation of implantation ease, operative time, and post-operative complications.
  • Short-term pharmacokinetic assessment.

    • Main Results:

    • The prosthetic shunts were easily implanted.
    • No anticoagulants were required for the shunts.
    • Operative time was decreased compared to standard procedures.
    • No evidence of thrombosis or venous stasis was observed.

    Conclusions:

    • The novel prosthetic portacaval shunt is effective and safe for short-term use.
    • The shunt simplifies surgical preparation and reduces operative time.
    • The device eliminates the need for anticoagulants and prevents associated complications.