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Transition Readiness Not Associated With Measures of Health in Youth With IBD
Marina Arvanitis1,2, Laura C Hart1,2, Darren A DeWalt1
1Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Insights
Transition readiness in pediatric and young adult inflammatory bowel disease (IBD) patients is linked to older age and female sex. Physical, psychological, and social health showed minimal associations with transition readiness in this IBD population.
Area of Science:
- Pediatric Gastroenterology
- Adolescent Health
- Inflammatory Bowel Disease (IBD) Research
Background:
- Transition readiness in pediatric and young adult patients with Inflammatory Bowel Disease (IBD) remains poorly understood.
- The association between transition readiness and various health domains requires further investigation.
Purpose of the Study:
- To describe transition readiness in children and young adults with IBD.
- To examine associations between transition readiness and demographic factors, IBD activity, and physical, psychological, and social health.
Main Methods:
- Utilized data from 2 internet-based cohorts sponsored by the Crohn's & Colitis Foundation.
- Recruited participants aged 12-20 years, collecting self-reported data on demographics, IBD activity, transition readiness, and health-related quality of life.
- Assessed physical, psychological, and social health using Patient-Reported Outcomes Information Systems (PROMIS) measures.
Main Results:
- Older age and female sex were associated with transition readiness, particularly in the pediatric cohort.
- IBD remission was linked to worse transition readiness in the pediatric group (beta = 0.3; P = 0.003).
- Physical health, fatigue, pain, and sleep disturbance showed no association with transition readiness. Small associations were found between transition readiness and anxiety in adults and peer relationships in children.
Conclusions:
- Transition readiness in pediatric and young adult IBD patients is associated with older age and female sex.
- Associations between transition readiness and physical, psychological, and social health were minimal, inconsistent, or absent across age groups.
Background:
It remains unclear how transition readiness is associated with various domains of health in children and young adults. Our objective was to describe the transition readiness of children and young adults with inflammatory bowel disease (IBD) and examine its associations with demographic factors, IBD activity, and measures of physical, psychological, and social health.
Methods:
We recruited children ages 12 to 17 and young adults ages 18 to 20 from 2 internet-based cohorts sponsored by the Crohn's & Colitis Foundation. Participants self-reported demographics, IBD activity, transition readiness, health-related quality of life, and Patient-Reported Outcomes Information Systems domains of physical, psychological, and social health.
Results:
Among 361 pediatric and 119 adult participants, age and female sex were associated with transition readiness. The association was greater in the pediatric cohort. Having IBD in remission was associated with worse transition readiness in the pediatric cohort only (beta = 0.3; P = 0.003). Health-related quality of life and Patient-Reported Outcomes Information Systems measures of fatigue, pain interference, and sleep disturbance were not associated with transition readiness in either children or adults. We observed few small associations between psychological or social health and transition readiness. Better transition readiness was associated with greater anxiety in adults (beta = -0.02; P = 0.02) and greater peer relationships among children (beta = 0.01; P = 0.009).
Conclusions:
In children and young adults with IBD, transition readiness was associated with older age and female sex. Associations between transition readiness and physical, psychological, and social health were either small, inconsistent across age groups, or nonexistent.
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