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Updated: Dec 27, 2025

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Preoperative Testing for Urethroplasty is Not Associated With Outcomes-A NSQIP Study
Kirtishri Mishra1, Amanda Avila2, Amr Mahran1
1Case Western Reserve University School of Medicine, Cleveland, OH; University Hospitals Cleveland Medical Center - Urology Institute, Cleveland, OH.
Objective:
To assess the current practice of routine preoperative testing before urethroplasty and to determine if the results are clinically significant.
Methods:
Data was obtained from the National Surgical Quality Improvement Program (NSQIP) database. We identified 1527 patients who underwent urethroplasty from 2010 to 2017. Chi-square and one-way ANOVA tests were used to compare categorical and continuous variables, respectively. Multivariable logistic regression analyses were utilized to assess the rate of complications between testing groups.
Results:
A total of 8455 individual laboratory tests were performed on 1156 patients (average of 7 tests per patient), with only 959 labs (11.3%) showing abnormal results. Of the 1156 patients, 629 (54.4%) patients had at least one abnormal lab. Patients who had at least one abnormal preoperative lab were found to be significantly older (51.49 ± 16.57 years vs 48.14 ± 16.32 years; P < .001), and to be smokers (112 [17.8%] vs 63 [12%]; P = 0.005). Additionally, they were more likely to have diabetes mellitus (112 [17.8%] vs 63 [12%]; P < 0.001), dyspnea (18 [2.9%] vs 16 [3.0%]; P = .029), and ASA class ≥3 when compared to the group with normal preoperative labs. On a multivariable logistic regression, abnormal preoperative tests were not predictive of intra- or postoperative complications in patients with ASA ≤2 (n = 1112) when adjusted for age and race. In patients with ASA class ≥3, the only lab predictive of postoperative complications was an abnormal coagulation profile.
Conclusion:
Obtaining routine preoperative labs, especially in patients with ASA ≤2, does not affect postoperative outcomes in patients undergoing urethroplasty.
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