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MRI safety considerations during pregnancy.

Mark Lum1, A John Tsiouris1

  • 1Department of Radiology, New York Presbyterian Hospital, Weill Cornell Medical Center, 525 E 68th St, New York, NY 10065, United States of America.

Clinical Imaging
|February 29, 2020
PubMed
Summary

Magnetic resonance imaging (MRI) is increasingly used in pregnancy due to its safety profile. While no direct harms have been found, further research is needed, especially concerning gadolinium-based contrast agents.

Keywords:
Contrast agent safetyGBCA in pregnancyImaging in pregnancyMRI safety

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Area of Science:

  • Radiology
  • Obstetrics
  • Medical Imaging

Background:

  • Magnetic resonance imaging (MRI) use in pregnancy is increasing.
  • MRI offers detailed anatomical imaging without ionizing radiation.
  • Concerns exist regarding MRI and gadolinium-based contrast agent (GBCA) safety during pregnancy.

Purpose of the Study:

  • To review the current evidence on MRI safety in pregnancy.
  • To contextualize findings within existing medical guidelines.
  • To guide radiologists in advising patients and providers.

Main Methods:

  • Literature review of studies on MRI and GBCA use in pregnancy.
  • Analysis of safety data across different trimesters.
  • Comparison with current professional society guidelines.

Main Results:

  • No attributable harms have been demonstrated for MRI in any trimester.
  • A single study suggests a potential association between GBCA administration and increased neonatal mortality.
  • Prospective and longitudinal studies are currently lacking.

Conclusions:

  • MRI is considered safe in pregnancy, with no proven adverse effects.
  • GBCA use warrants careful consideration due to potential risks.
  • Radiologists play a key role in informed decision-making for pregnant patients undergoing MRI.