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Perceptions and Beliefs Regarding NSAIDs in the Asia-Pacific Region.
1The Pain Clinic, Mount Alvernia Hospital, Singapore.
Journal of Pain Research
|February 29, 2020
Summary
Patient and physician awareness of non-steroidal anti-inflammatory drug (NSAID) risks is low. Improved physician risk stratification is crucial to minimize adverse events associated with NSAID use.
Area of Science:
- Pharmacology
- Public Health
- Clinical Medicine
Background:
- Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for pain and inflammation.
- Chronic NSAID use poses risks, including gastrointestinal (GI), cardiovascular (CV), and renal concerns, particularly in high-risk individuals.
- Understanding perceptions of NSAID safety and efficacy is vital.
Purpose of the Study:
- To systematically review and organize evidence on physician and patient perceptions of NSAID safety and efficacy.
- To focus on the Asia-Pacific (APAC) region and cyclooxygenase-2 (COX-2) selective inhibitors.
Main Methods:
- Systematic literature search of MEDLINE (PubMed), Embase (Ovid), and Cochrane Library.
- Supplementary searches via Google Scholar and Google.
- Analysis included 99 studies, with a specific focus on 23 from the APAC region.
Main Results:
- A small fraction (3.5%) of retrieved studies met inclusion criteria.
- Commonly perceived risks involved GI, CV, renal, and respiratory safety.
- Efficacy and COX-2 inhibitors were also frequent topics of perception.
Conclusions:
- Patient awareness regarding NSAID risks is significantly lacking.
- Physicians should implement risk stratification to reduce adverse events.
- Further education and communication are needed to improve NSAID safety.
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