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Dexamethasone Implant Migration through an Iris Coloboma.

Yoav Glidai^1,2, Shulamit Schwartz^1,2, Eyal Cohen^1,2

¹Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel.

Case Reports in Ophthalmology

|February 29, 2020

Summary

Ozurdex implant migration through an iris coloboma caused corneal edema in a pseudophakic patient. This case highlights a novel surgical approach for dexamethasone implant removal from the anterior chamber.

Keywords:

Implant Iris coloboma Migration Ozurdex Surgical technique

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Area of Science:

Ophthalmology
Retinal Diseases
Ocular Surgery

Background:

Ozurdex (dexamethasone 0.7 mg implant) is used for cystoid macular edema.
Implant migration to the anterior chamber is an uncommon complication, potentially causing irreversible corneal edema.
Risk factors include defective lens capsule or prior vitrectomy.

Observation:

A 56-year-old pseudophakic male with a congenital iris coloboma presented with decreased vision 8 weeks post-Ozurdex injection.
Diagnosis was corneal edema due to implant migration through the iris coloboma.
The patient had an intact posterior lens capsule.

Findings:

This is the first reported case of Ozurdex implant migration through an iris coloboma with an intact posterior capsule.
Surgical intervention successfully resolved corneal edema within 2 weeks.
A novel, simple, and efficient surgical approach for anterior chamber implant removal was utilized.

Implications:

Congenital iris coloboma can be a risk factor for Ozurdex implant migration.
Early surgical intervention is crucial for managing implant migration complications.
The described surgical technique offers an effective solution for removing migrated intraocular implants.