Study of correlation of urodynamic profile with symptom scoring and ultrasonographic parameters in patients with...

Urodynamic study (UDS) and ultrasonography (USG) both are established investigations to assess the patients of benign prostatic hyperplasia (BPH). It is known that the prostate mass (PM) and post-void residual urine volume (PVR) are not significantly related to the patients' symptoms and degree of obstruction; however, the relation between the UDS, USG and patient's International Prostate Symptom Scoring (IPSS) has not been defined.

To correlate the urodynamic parameters with IPSS, PM and PVR in patients with lower urinary tract symptoms (LUTS) suggestive of BPH.

An observational study carried out as a thesis project.

Thirty male patients aged more than 40 years with LUTS suggestive of BPH were selected and underwent USG, UDS and IPSS. In UDS, the parameters studied were the maximum flow rate (Q_max), detrusor pressure (P_det) and bladder compliance (BC). PM and PVR were studied in the USG.

IBM Statistical Package for the Social Sciences (SPSS) software version 16 (SPSS Inc., Chicago, USA). Pearson's correlation and two-sided significance levels were determined.

1. Significant negative correlation between Q_max and PVR_USG (r = -0.404, P = 0.027); PM_USG (r = -0.655, P = <0.001) and IPSS (r = -0.563, P = 0.001). 2. Significant positive correlation between P_det and PVR_USG (r = 0.535, P = 0.002); PM_USG (r = 0.719, P = <0.001) and IPSS (r = 0.649, P = <0.001). 3. Significant negative correlation between BC and PVR_USG (r = -0.490, P = 0.006); PM_USG (r = -0.654, P = <0.001) and IPSS (r = -0.667, P = <0.001).

UDS has a significant correlation with IPSS and USG findings and urodynamic parameters give a more specific diagnosis in BPH patients when it is combined with USG and IPSS.