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Updated: Dec 27, 2025
Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Crestal bone loss around dental implants after implantation of Tricalcium phosphate and Platelet- Rich Plasma: A
Sravani Uppala1, Anuj Singh Parihar2, Varsha Modipalle3
1Department of Conservative Dentistry and Endodontics, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinaoutpalli, Andhra Pradesh, India.
Background And Aims:
Bone loss around dental implants is generally measured by monitoring changes in marginal bone level using radiographs. After the first year of implantation, an implant should have <0.2 mm annual loss of marginal bone level to satisfy the criteria of success. However, the success rate of dental implants depends on the amount of the crestal bone around the implants. The main aim of this study was to evaluate and compare the crestal bone loss around implants placed with particulate β-Tricalcium Phosphate Bone Graft and platelet concentrates.
Methods:
50 individuals received hundred dental implants. Each individual received one dental implant in the edentulous site filled with β-Tricalcium Phosphate Bone Graft along (β-TCP) with Platelet- Rich Plasma (PRP) (Group A) and another in edentulous site filled only with β-Tricalcium Phosphate Bone Graft (Group B) in the posterior edentulous region. All the 100 implants were prosthetically loaded after a healing period of three months. Crestal bone loss was measured on mesial, distal, buccal and lingual side of each implant using periapical radiographs 3 months, 6 months and 9 months after implant placement.
Results:
The average crestal bone loss 9 months after the implants placement in Group A and Group B was 2.75 mm and 2.23 mm respectively, the value being statistically significant (P < 0.05). In both Group A and Group B, the average crestal bone loss was maximum on the lingual side followed by buccal, distal and mesial sides.
Conclusion:
β-TCP is a promising biomaterial for clinical situations requiring bone augmentation. However, the addition of PRP results in decreased bone loss around the dental implants.
