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Comparative Cost-Effectiveness of Cranioplasty Implants.

Adam Binhammer1, Josie Jakubowski1, Oleh Antonyshyn1,2

  • 1Department of Plastic and Reconstructive Surgery, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Plastic Surgery (Oakville, Ont.)
|February 29, 2020
PubMed
Summary

Manually shaped titanium mesh offers the most cost-effective cranioplasty for small defects. While autogenous bone or titanium mesh suits larger defects, PMMA and PEEK implants are significantly more expensive.

Keywords:
PEEKPMMAautogenous bonecostcranioplastyoperative timetitanium implants

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Area of Science:

  • Neurosurgery
  • Medical Device Materials
  • Health Economics

Background:

  • Cranioplasty is a surgical procedure to repair skull defects.
  • Material choice impacts operative duration and hospital costs.
  • Evaluating cost-effectiveness of various cranioplasty implants is crucial for clinical decision-making.

Purpose of the Study:

  • To compare operative duration and total hospital costs for elective cranioplasty using diverse materials.
  • Materials evaluated include autogenous bone graft, titanium mesh (manually shaped and custom), PMMA, and PEEK.

Main Methods:

  • Retrospective chart review at a single center.
  • Data collected: patient demographics, defect characteristics, operative time, and hospital stay.
  • Cost data standardized to 2014-2015; bivariate and multivariate analyses performed.

Main Results:

  • Autogenous implants showed longer operative time (178 min) than manual titanium (P < .01).
  • Manual titanium cost: $18,335; custom titanium: $31,956; PMMA: $20,786; autogenous: $14,291; PEEK: $27,379 (P = .013).
  • PMMA and PEEK implants incurred significantly higher costs than manual titanium (P < .01).

Conclusions:

  • Manually shaped titanium mesh is the most cost-effective for small cranial defects.
  • Autogenous bone or titanium mesh is best for large or complex defects (e.g., frontal paranasal sinus).
  • PMMA and PEEK implants are significantly more costly, potentially due to higher complication rates.