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Updated: Dec 27, 2025

Engineering Platform and Experimental Protocol for Design and Evaluation of a Neurally-controlled Powered Transfemoral Prosthesis
Published on: July 22, 2014
Adaptive multichannel FES neuroprosthesis with learning control and automatic gait assessment
Philipp Müller1, Antonio J Del Ama2, Juan C Moreno3
1Technische Universität Berlin, Berlin, Germany. mueller@control.tu-berlin.de.
This study developed a learning full-leg neuroprosthesis for individuals with spinal cord injuries, demonstrating its ability to create personalized stimulation patterns and improve gait parameters like knee and foot angles.
Area of Science:
- Biomedical Engineering
- Neurorehabilitation
- Robotics
Background:
- Functional Electrical Stimulation (FES) neuroprostheses aid stroke and Spinal Cord Injury (SCI) patients in gait rehabilitation.
- Previous systems required manual tuning and lacked individual adaptation.
- Recent advancements include learning controllers for adaptive stimulation patterns.
Purpose of the Study:
- To develop a learning full-leg neuroprosthesis for adaptive gait support in SCI individuals.
- To control knee and ankle joint movements through antagonistic muscle stimulation.
- To enable continuous gait phase assessment and personalized rehabilitation.
Main Methods:
- Established a continuous assessment method for knee and foot joint angles during gait.
- Developed a novel Iterative Learning Controller (ILC) independent of step duration.
- Utilized physiological joint angle reference bands for gait pattern warping and comparison.
Main Results:
- The neuroprosthesis successfully generated individually fitted stimulation patterns for 3 out of 4 incomplete SCI participants.
- Two participants showed slight improvements in average foot angles (up to 4°).
- One participant exhibited slight improvements in average knee angles (up to 4°).
Conclusions:
- The proposed method allows direct adaptation to individual gait patterns.
- Preliminary tests confirm the neuroprosthesis's capability to generate personalized stimulation.
- Future work will address sensitivity to knee angle resets, gait fluctuations, and ILC gain tuning.
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