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Updated: Dec 27, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Differences in Risk Factors for Melanoma in Young and Middle-aged Higher-risk Patients
Johanna S Palve1, Niina J Korhonen2, Tiina H Luukkaala3
1Department of Plastic Surgery, Faculty of Medicine and Health Technology and Tampere University Hospital, Tampere University, Tampere, Finland johanna.palve@pshp.fi.
Background/Aim:
Differences in risk factors for melanoma between young adults (18-39 years) and middle-aged (40-60 years) are not well documented. In this study, we aimed to determine differences in risk factors and characteristics of melanoma between these groups.
Patients And Methods:
This retrospective study is a review on 330 patients, including 250 middle-aged and 80 young adults, during the period 2006-2016 in the Tampere university hospital, in Finland.
Results:
Forty-one per cent of middle-aged and 47% of young adults were defined as higher-risk patients. High nevus count was the most common host risk factor in both groups. Young were more likely to have a family history of melanoma. Middle-aged had more often excessive intermittent sun exposure and a history of sunburn. Host risk characteristics were less commonly associated with thicker melanomas.
Conclusion:
A high number of patients have host risk factors for melanoma. Several differences exist in risk factors and characteristics of melanomas between young adults and middle-aged patients.
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