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A Case Series of Children With 2019 Novel Coronavirus Infection: Clinical and Epidemiological Features

Cai Jiehao1, Xu Jin2, Lin Daojiong3

  • 1Department of Infectious Diseases, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|March 1, 2020
PubMed

Insights

This study details 2019 novel coronavirus infections in 10 children outside Wuhan. Pediatric cases often present mildly, with exposure history being crucial for diagnosis, and prolonged shedding occurs in respiratory and fecal matter.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Epidemiology

Background:

  • The 2019 novel coronavirus (COVID-19) emerged as a significant global health threat.
  • Understanding the clinical presentation and epidemiological characteristics of COVID-19 in children is crucial.

Purpose of the Study:

  • To describe the initial cases of 2019 novel coronavirus infection in pediatric patients outside of Wuhan.
  • To highlight key clinical and epidemiological features of pediatric COVID-19.

Main Methods:

  • Retrospective case series.
  • Clinical data collection from 10 pediatric patients diagnosed with 2019 novel coronavirus infection.
  • Epidemiological investigation of exposure history.

Main Results:

  • The 10 pediatric cases occurred in areas distinct from Wuhan.
  • Coronavirus disease in these children was generally mild.
  • Epidemiological exposure history was a significant factor in case identification.
  • Prolonged shedding of the virus was detected in respiratory secretions and feces during the convalescent phase.

Conclusions:

  • Pediatric 2019 novel coronavirus infections can occur outside major outbreak centers.
  • Mild clinical presentation is common in children, underscoring the importance of epidemiological links.
  • Extended virus shedding in respiratory and fecal samples has implications for transmission and infection control in pediatric populations.

Keywords:
2019 novel coronaviruschildrencoronavirus diseases

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