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Updated: Dec 27, 2025

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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
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Venous flow patterns after percutaneous atrial septal defect closure: Does the mechanical device decrease right
Amitabh Poonia1, Priya Giridhara1, Sivasankaran Sivasubramonian1
1Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India.
Echocardiography (Mount Kisco, N.Y.)
|March 1, 2020
Summary
Percutaneous closure of atrial septal defects (ASDs) improves systemic venous flow, especially in larger defects. Follow-up reveals progressive enhancement of diastolic flow over six months.
Area of Science:
- Cardiology
- Medical Devices
- Vascular Physiology
Background:
- Surgical closure of ostium secundum atrial septal defects (ASDs) can lead to abnormal systemic venous flow.
- Systemic venous flow changes after percutaneous ASD closure are not well-studied.
Purpose of the Study:
- To investigate systemic venous Doppler flow patterns after percutaneous closure of ASD.
- To correlate these changes with defect and device size.
Main Methods:
- Prospective documentation of systemic venous Doppler flow patterns in 50 subjects.
- Measurements taken before, immediately after, and at 6-month follow-up.
- Correlation with defect and device size.
Main Results:
- Increased forward flow velocity (systolic and diastolic) in hepatic veins and superior vena cava post-closure.
- Significant increase in the diastolic/systolic (D/S) flow ratio, indicating improved atrial filling.
- Changes were more pronounced and statistically significant in patients with larger defect sizes (≥15 mm/sq.m).
Conclusions:
- Percutaneous ASD closure positively impacts systemic venous flow dynamics.
- Larger defects and devices are associated with more significant flow changes.
- Persistent abnormalities warrant follow-up for potential atrial remodeling and arrhythmias.

