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Restless legs syndrome among multiple sclerosis patients in Lebanon
J Makhoul1, N Ghaoui1, G Sleilaty2
1Department of Neurology, Hôtel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Multiple Sclerosis and Related Disorders
|March 1, 2020
Summary
Restless Legs Syndrome (RLS) affects 15% of multiple sclerosis (MS) patients in Lebanon. Early RLS evaluation is crucial for improving the quality of life in MS patients.
Area of Science:
- Neurology
- Sleep Medicine
- Radiology
Background:
- Multiple sclerosis (MS) is frequently linked to fatigue and a higher incidence of sleep disorders, particularly Restless Legs Syndrome (RLS).
- RLS is a common neurological disorder characterized by an urge to move the legs, often accompanied by uncomfortable sensations.
Purpose of the Study:
- To determine the prevalence and severity of RLS in Lebanese MS patients.
- To investigate the co-occurrence of RLS with spinal demyelination lesions in this population.
Main Methods:
- A cross-sectional study involving 300 MS patients in Lebanon, screening for RLS using questionnaires.
- Confirmed RLS cases (n=28) underwent further evaluation for comorbidities, spinal MRI, and disease severity using the EDSS and JHRLSS.
Main Results:
- RLS prevalence was 15% among the studied MS patients.
- Nearly half (46.4%) of MS patients with RLS exhibited spinal cord demyelination lesions on MRI.
- A trend suggested lower JHRLSS scores in patients with MRI lesions (p=0.088).
Conclusions:
- RLS is prevalent and often underdiagnosed in Lebanese MS patients.
- Systematic RLS screening is recommended to enhance patient quality of life.
- Further research may explore the relationship between RLS, spinal lesions, and MS severity.
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