Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Layers of Connective Tissue Proper01:21

Layers of Connective Tissue Proper

3.2K
Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing...
3.2K
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

2.6K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
2.6K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

1.6K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.6K
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

1.8K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
1.8K
Peripherally and Centrally Acting Muscle Relaxants: A Comparison01:09

Peripherally and Centrally Acting Muscle Relaxants: A Comparison

4.3K
Skeletal muscle relaxants can target the central nervous system [CNS] to reduce muscle tension or act directly at the neuromuscular junction to induce temporary paralysis. These two classes of muscle relaxants are called centrally acting muscle relaxants and peripherally acting muscle relaxants. They differ in their action, mechanism, administration route, and clinical uses.
Centrally acting muscle relaxants can be further divided into spasmolytic and antispasmodic drugs. Spasmolytic...
4.3K
Skeletal Muscle Relaxants: Adverse Effects01:21

Skeletal Muscle Relaxants: Adverse Effects

726
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
726

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing Graduate Surgical Education: Recommendations for Development of Common Surgery Education and Training Accreditation Standards.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches·2026
Same author

Principles of Microsurgery.

Clinics in plastic surgery·2025
Same author

Management of the Mutilating Upper Extremity Injury.

Clinics in plastic surgery·2025
Same author

Pediatric Microsurgery Part I.

Clinics in plastic surgery·2025
Same author

Pediatric Microsurgery Part II.

Clinics in plastic surgery·2025
Same author

Technology in Microsurgery.

Clinics in plastic surgery·2025
Same journal

Lower-Extremity Reconstruction: Principles, Progress, and Perspectives.

Clinics in plastic surgery·2026
Same journal

Pediatric.

Clinics in plastic surgery·2026
Same journal

Lower Extremity Reconstruction in Acute Burns.

Clinics in plastic surgery·2026
Same journal

Chronic Lower Extremity Wounds: Updates on Lower Extremity Reconstruction in Clinics in Plastic Surgery.

Clinics in plastic surgery·2026
Same journal

Updates in Lower Extremity Reconstruction: Post Sarcoma.

Clinics in plastic surgery·2026
Same journal

Fillet Flaps for Lower Extremity Salvage.

Clinics in plastic surgery·2026
See all related articles

Related Experiment Video

Updated: Dec 27, 2025

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K

Fibromyalgia.

Michael W Neumeister1, Evyn L Neumeister2

  • 1Department of Surgery, Institute for Plastic Surgery, Southern Illinois University School of Medicine, 747 North Rutledge Suite 357, Baylis Building, Springfield, IL 62702, USA.

Clinics in Plastic Surgery
|March 3, 2020
PubMed
Summary
This summary is machine-generated.

Fibromyalgia, a condition causing widespread pain and fatigue, presents diagnostic challenges for surgeons. Careful patient history is crucial to differentiate fibromyalgia symptoms from surgical conditions for appropriate pain management.

Keywords:
Central sensitizationChronic painFibromyalgiaPainPain disorders

More Related Videos

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

5.8K
Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

725

Related Experiment Videos

Last Updated: Dec 27, 2025

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
08:33

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

1.6K
Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
07:19

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

Published on: March 24, 2023

5.8K
Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

725

Area of Science:

  • Pain Medicine
  • Rheumatology
  • Surgical Diagnosis

Background:

  • Fibromyalgia is a complex chronic pain disorder with diverse symptoms including fatigue, sleep, and cognitive issues.
  • The epidemiology and diagnostic criteria for fibromyalgia remain incompletely understood.
  • Managing pain in fibromyalgia patients can be challenging, complicating surgical decision-making.

Purpose of the Study:

  • To highlight the diagnostic difficulties surgeons face when evaluating patients with fibromyalgia.
  • To emphasize the importance of a thorough medical history in surgical candidates with fibromyalgia.
  • To guide surgeons in differentiating fibromyalgia symptoms from true surgical conditions.

Main Methods:

  • Review of clinical characteristics of fibromyalgia.
  • Analysis of diagnostic challenges in surgical patients with fibromyalgia.
  • Emphasis on differential diagnosis in pain management.

Main Results:

  • Fibromyalgia symptoms can mimic or obscure distinct surgical pathologies.
  • Distinguishing heightened sensitivity in fibromyalgia from surgical pain requires meticulous evaluation.
  • Surgical intervention may not be suitable for all pain presentations in fibromyalgia patients.

Conclusions:

  • Surgeons must exercise caution when diagnosing and treating fibromyalgia patients.
  • A comprehensive understanding of the patient's medical history is paramount for surgical success.
  • Careful assessment can prevent inappropriate surgical interventions for fibromyalgia-related pain.