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Related Concept Videos

Ischemic Heart Disease: Overview01:17

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
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Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
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Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
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Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
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Ischemic Pain.

Michael R Romanelli1, Jacob A Thayer1, Michael W Neumeister1

  • 1Department of Surgery, Institute for Plastic Surgery, Southern Illinois University School of Medicine, 747 North Rutledge Street, 3rd Floor, PO Box 19653, Springfield, IL 62794-9653, USA.

Clinics in Plastic Surgery
|March 3, 2020
PubMed
Summary
This summary is machine-generated.

This article explains ischemic pain in surgical patients, detailing its causes, how it

Keywords:
IschemiaIschemic painIschemic surgical pain

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Area of Science:

  • Surgical Medicine
  • Pain Management
  • Vascular Surgery

Background:

  • Ischemic pain arises from inadequate blood flow to tissues, leading to local acidosis.
  • This acidosis triggers pain signals transmitted via ascending pathways to the brain.
  • Understanding pathophysiology is crucial for effective surgical patient management.

Purpose of the Study:

  • To comprehensively review the pathophysiology, presentation, causes, and treatment of ischemic pain in surgical patients.
  • To highlight the role of local acidosis in the perception of ischemic pain.
  • To outline current and potential therapeutic strategies.

Main Methods:

  • Review of existing literature on ischemic pain in the surgical context.
  • Discussion of the neurophysiological pathways involved in pain signal transmission.
  • Categorization of treatment modalities, including surgical and conservative options.

Main Results:

  • Ischemic pain results from peripheral tissue acidosis due to impaired perfusion.
  • Pain signals ascend to the thalamus and cerebral cortex for interpretation.
  • Onset can be insidious, acute, or chronic.

Conclusions:

  • Effective treatment of ischemic pain necessitates improving tissue perfusion.
  • Surgical interventions like vessel repair, bypass, thrombectomy, or embolectomy are key options.
  • A range of conservative therapies should also be considered.