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Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

654
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
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Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

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Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
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Assessment of Ventilation II: Respiratory Depth and Rhythm01:29

Assessment of Ventilation II: Respiratory Depth and Rhythm

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Respiratory Depth
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
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Related Experiment Video

Updated: Dec 27, 2025

Author Spotlight: Advancing 3D Modeling for Enhanced Diagnosis and Treatment of Pulmonary Nodules in Early-Stage Lung Cancer
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An open-source framework for pulmonary fissure completeness assessment.

James C Ross1, Pietro Nardelli1, Jorge Onieva2

  • 1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society
|March 3, 2020
PubMed
Summary
This summary is machine-generated.

We developed an open-source framework to assess pulmonary fissure completeness, crucial for understanding emphysema treatment. This tool aids researchers by providing accurate fissure and lung lobe boundary analysis.

Keywords:
Fissure completenessLung lobe fissures

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Area of Science:

  • Medical Imaging
  • Computational Anatomy
  • Pulmonary Medicine

Background:

  • Pulmonary fissure incompleteness is linked to emphysema treatment outcomes.
  • Accurate fissure detection and lung lobe segmentation are essential for completeness assessment.
  • Existing methods for these tasks are diverse and evolving.

Purpose of the Study:

  • To introduce an open-source framework for pulmonary fissure completeness assessment.
  • To provide a modular and deployable tool for analyzing lung lobe segmentation and fissure detection data.
  • To facilitate research on the association between fissure completeness and emphysema treatment.

Main Methods:

  • Developed a framework with a quality control module for segmentation assessment.
  • Integrated an interactive 3D Slicer tool for challenging segmentation cases.
  • Employed a particle-based sampling for fissure representation and voxel counting/surface area estimation for completeness analysis.

Main Results:

  • The framework was successfully deployed on 100 diverse cases.
  • Two distinct completeness estimation approaches were compared.
  • The framework's results were compared against visual assessments.

Conclusions:

  • The presented framework offers a flexible and deployable solution for pulmonary fissure completeness assessment.
  • The open-source nature facilitates community adoption and further development.
  • This tool can advance research into the clinical significance of fissure completeness in emphysema.