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Updated: Dec 27, 2025

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Correlation Between Echocardiographic and Hemodynamic Variables in Cardiothoracic Intensive Care Unit
Guido Tavazzi1, Valentino Dammassa1, Francesco Corradi2
1Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Anaesthesia and Intensive Care Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Mitral annular plane systolic excursion (MAPSE) and left ventricular total isovolumic time (t-IVT) reliably assess hemodynamic function in critically ill patients. Left ventricular ejection fraction (LVEF) was not found to be a reliable indicator in this population.
Area of Science:
- Cardiology
- Critical Care Medicine
- Echocardiography
Background:
- Echocardiographic indices require validation in critically ill populations.
- Hemodynamic monitoring is crucial for managing severe circulatory and respiratory failure.
Purpose of the Study:
- To investigate the correlation between echocardiographic indices and hemodynamic parameters in critically ill patients.
- To determine the reliability of echocardiographic measures for assessing ventricular function in this population.
Main Methods:
- A prospective, observational study was conducted in an adult cardiothoracic intensive care unit.
- 117 critically ill patients with severe respiratory or cardiocirculatory failure, or post-aortic surgery, were included.
- Echocardiographic indices (t-IVT, MAPSE, LVEF) and hemodynamic parameters (SV, CO, MAP, CPI) were evaluated.
Main Results:
- t-IVT showed inverse correlations with SV, CO, MAP, and CPI (r -67% to -51%).
- MAPSE demonstrated positive correlations with SV, CO, MAP, and CPI (r 31% to 44%).
- LVEF did not correlate with hemodynamic parameters; t-IVT and MAPSE showed reproducible associations.
Conclusions:
- MAPSE and t-IVT are reproducible and reliable echocardiographic indices for assessing systolic function and ventricular efficacy in cardiothoracic critically ill patients.
- These indices are associated with key hemodynamic variables.
- LVEF was not found to be a reliable correlate of hemodynamic status in this cohort.
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