Related Experiment Video
Updated: Dec 27, 2025
Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
Portable Hg2+ Nanosensor with ppt Level Sensitivity Using Nanozyme as the Recognition Unit, Enrichment Carrier, and
Yumeng Fang1,2, Yue Zhang1, Leigang Cao2
1Functional Nanomaterials Laboratory, Centre for Micro/Nanomaterials and Technology and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Zhongguancundonglu 29, Haidianqu, Beijing 100190, China.
Abstract:
We report a portable and highly sensitive Hg2+ nanosensor, where the CuS nanozyme functions as an Hg2+ recognition unit, a Hg2+ enrichment/preconcentration carrier, and a signal amplifier/output unit. The as-designed enrichment-detection integration strategy is customizable and endows the sensor with both a wide detection range from 50 ppt to 400 ppb and a high sensitivity with a minimum detectable Hg2+ concentration of 50 ppt. In order to make the Hg2+ nanosensor portable and cost-effective, a commercial RGB sensor is employed here in conjunction with the Hg2+-dependent colorimetric reaction. More importantly, the as-developed Hg2+ nanosensor is feasible for analysis of real samples with satisfactory accuracy (deviation <10%) and reproducibility (recovery ∼82%). Thus, this portable Hg2+ nanosensor appears to be a viable solution to meet the actual needs of on-site and real-time mercury contamination analysis and may also pave the way to colorimetric nanosensors for other metal ions.
More Related Videos
07:10Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis
Published on: July 8, 2025
07:16Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
Published on: February 9, 2024