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Desmetramadol Is Identified as a G-Protein Biased µ Opioid Receptor Agonist

John A Zebala1, Aaron D Schuler1, Stuart J Kahn1

  • 1Department of Chemistry and Preclinical Development, Syntrix Pharmaceuticals, Auburn, WA, United States.

Frontiers in Pharmacology
|March 3, 2020
PubMed

Keywords:
CYP2D6O-desmethyltramadolbiased agonistsfentanylopioid crisisrespiratory depressiontramadolβarrestin

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