Striatum-Mediated Deficits in Stimulus-Response Learning and Decision-Making in OCD

Nole M Hiebert1,2,3, Marc R Lawrence3, Hooman Ganjavi4

  • 1Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.

Summary

Patients with obsessive compulsive disorder (OCD) show impaired decision-making and learning. Their brains exhibit reduced activity in the dorsal striatum (DS) and ventral striatum (VS), highlighting striatal dysfunction in OCD.

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