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Related Experiment Video

Updated: Dec 27, 2025

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

Basal and Infectious Enteritis in Broilers Under the I See Inside Methodology: A Chronological Evaluation.

Adrien W D Sanches¹, Bruna L Belote¹, Paulo Hümmelgen¹

¹Laboratório de Microbiologia e Ornitopatologia, Universidade Federal do Paraná, Curitiba, Brazil.

Frontiers in Veterinary Science

|March 3, 2020

Summary

Microscopic enteritis (ME) in chickens can now be described using the I See Inside (ISI) methodology, distinguishing basal and infectious enteritis. This model links intestinal inflammation to performance losses, aiding poultry health management.

Keywords:

ISI basal enteritis inflammatory chronology microscopic enteritis regenerative inflammation

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Last Updated: Dec 27, 2025

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Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Published on: November 6, 2013

Area of Science:

Veterinary Pathology
Avian Medicine
Gastroenterology

Background:

Intestinal mucosal inflammation is linked to various diseases in humans and animals.
A veterinary counterpart to human Microscopic Enteritis (ME) classification is lacking.
The I See Inside (ISI) methodology offers a novel approach to avian ME assessment.

Purpose of the Study:

To describe the development of avian Microscopic Enteritis (ME) using the I See Inside (ISI) methodology.
To differentiate between basal enteritis and infectious enteritis in chickens.
To correlate ISI parameters with zootechnical performance losses.

Main Methods:

Two trials involving 64 chickens each, divided into non-challenged and challenged groups (Eimeria spp. and Clostridium perfringens).
Chickens were euthanized at specific ages (7, 14, 21, 28 days) for ileum and liver sample collection.
ISI evaluation, cytokine analysis, and immune cell presence (macrophages, CD4+, CD8+) were assessed.

Main Results:

The ISI methodology successfully described avian ME, identifying two components: basal enteritis (BE) and infectious enteritis.
A clear chronology of ME development was observed through ISI parameters in challenged birds.
ISI parameters were significantly associated with losses in zootechnical performance.

Conclusions:

The ISI methodology provides a comprehensive tool for understanding avian Microscopic Enteritis.
This approach allows for the characterization of distinct enteritis types and their progression.
The findings highlight the impact of enteritis on poultry productivity and offer avenues for improved disease management.