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Related Experiment Videos

Widespread cutaneous vasculitis associated with diltiazem.

R A Sheehan-Dare1, M J Goodfield

  • 1Department of Dermatology, General Infirmary, Leeds, UK.

Postgraduate Medical Journal
|June 1, 1988
PubMed
Summary

Diltiazem, a calcium antagonist, was linked to widespread skin vasculitis in two patients. Symptoms resolved naturally after discontinuing the medication.

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Area of Science:

  • Cardiology
  • Dermatology
  • Pharmacology

Background:

  • Diltiazem is a recently introduced calcium channel blocker.
  • Cutaneous vasculitis is an inflammatory condition affecting skin blood vessels.

Observation:

  • Two cases of widespread cutaneous vasculitis were observed.
  • Both cases were associated with the use of diltiazem.

Findings:

  • Spontaneous resolution of vasculitis occurred in both patients.
  • Resolution took place over several weeks after diltiazem withdrawal.

Implications:

  • Diltiazem may be associated with cutaneous vasculitis.
  • Drug-induced vasculitis should be considered in patients using diltiazem.
  • Discontinuation of diltiazem can lead to resolution of symptoms.

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