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Multidrug-Resistant Escherichia coli Canaliculitis
Oshin Bansal1, Nandini Bothra, Savitri Sharma
1Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, India.
Ophthalmic Plastic and Reconstructive Surgery
|March 3, 2020
Summary
Escherichia coli canaliculitis is rare, with this case showing resistance to standard treatment. The infection may stem from a urinary tract source, suggesting autoinoculation.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Primary canaliculitis is typically caused by bacteria other than Escherichia coli.
- Recurrent urinary tract infections (UTIs) are common in some patient populations.
Observation:
- A case of unilateral canaliculitis resistant to conventional therapy is presented.
- The patient had a history of recurrent, culture-proven Escherichia coli UTIs.
- Microbiological analysis confirmed E. coli in the affected canaliculus.
Findings:
- Histological examination revealed goblet cell metaplasia, subepithelial edema, and inflammatory infiltrate.
- Escherichia coli was identified as the causative agent of the canaliculitis.
- The clinical presentation was refractory to standard treatment protocols.
Implications:
- This case highlights the potential for Escherichia coli to cause primary canaliculitis.
- Endogenous infection or autoinoculation from a UTI is a possible transmission route.
- Further investigation into non-conventional treatment strategies for refractory E. coli canaliculitis may be warranted.
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