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Determination of drugs containing fluorine with ion-selective electrode. Part 1: Synthetic glucocorticosteroids
1Department of Medicinal Chemistry, Medical Academy, Lublin, Poland.
Die Pharmazie
|June 1, 1988
Abstract:
Synthethic glucocorticosteroids (fludrocortisone acetate, fluocinolone acetate, flumethasone pivalate, triamcinolone acetonide and dexamethasone acetate) were determined on the basis of their fluoride content, when deflagrated after Schöniger, in three ways: by potentiometric titration or by direct potential measurement of ion-selective fluoride electrode or by spectrophotometry with lanthanum alizarin complexan.
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