A virtual reality paradigm to assess episodic memory: Validation-dataset for six parallel versions and a structured...

Area of Science:

• Neurology
• Cognitive Neuroscience
• Medical Technology

Background:

• Epilepsy monitoring units (EMUs) require reliable tools to assess cognitive function.
• Episodic memory is frequently affected in epilepsy and by antiepileptic drugs.
• Virtual reality (VR) offers immersive environments for cognitive testing.

Purpose of the Study:

• To validate parallel versions of a VR test for episodic memory in an EMU setting.
• To assess the feasibility of using VR for monitoring memory in epilepsy patients.
• To evaluate the test's potential for detecting effects of seizures or medication on memory.

Main Methods:

• Twenty adult epilepsy patients were recruited in an EMU.
• A VR episodic memory test with 6 parallel versions was administered up to 7 times per patient.
• Testing included immediate recall, delayed recall, and recognition memory, assessing various recall sub-scales.

Main Results:

• Data from 9 patients provided a full 7-session dataset for immediate recall.
• The VR test demonstrated feasibility for use within the EMU environment.
• Patient medication status was controlled (off-medication or stable medication).

Conclusions:

• The VR episodic memory test is a feasible tool for use in epilepsy monitoring units.
• This technology can potentially monitor cognitive effects of seizures and antiepileptic medication.
• Further research can explore VR's application in longitudinal memory assessments in epilepsy.