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ART in Europe, 2015: results generated from European registries by ESHRE
C De Geyter1,2, C Calhaz-Jorge3, M S Kupka4
1Reproductive Medicine and Gynaecological Endocrinology (RME), University Hospital, University of Basel, Basel, Switzerland.
Human Reproduction Open
|March 4, 2020
Summary
European assisted reproductive technology (ART) and intrauterine insemination (IUI) treatments expanded in 2015. While pregnancy rates slightly decreased for IVF and ICSI, frozen embryo replacement (FER) saw an increase, indicating ART's growing impact.
Area of Science:
- Reproductive Medicine
- Public Health
- European Healthcare Trends
Background:
- The European IVF-Monitoring Consortium (EIM) for ESHRE has collected ART data since 1997.
- Annual reports track European assisted reproductive technology (ART) and intrauterine insemination (IUI) trends.
- The 19th EIM report details 2015 data from 38 European countries.
Purpose of the Study:
- To analyze European trends and developments in ART and IUI for 2015.
- To compare 2015 ART and IUI data with previous years.
- To assess the impact of ART on European society.
Main Methods:
- Data collected from 1343 institutions offering ART and 1352 institutions offering IUI across 38 European countries.
- Included 849,811 ART cycles (IVF, ICSI, FER, PGT, ED, IVM, FOR) and 188,051 IUI cycles (IUI-H, IUI-D).
- Analysis focused on treatment numbers, pregnancy rates (PRs), and delivery rates (DRs).
Main Results:
- A total of 409,771 ART cycles were reported in 18 countries, with 1432 cycles per million inhabitants.
- Clinical pregnancy rates per aspiration/transfer slightly decreased for IVF and ICSI in 2015 compared to 2014.
- Frozen embryo replacement (FER) PR per thawing increased to 29.2%, while egg donation (ED) PR slightly decreased.
- Delivery rates for IUI remained stable (IUI-H: 7.8%, IUI-D: 12.0%).
- Embryo transfer trends shifted towards fewer embryos, resulting in higher singleton DR (83.1%) and lower twin/triplet DRs.
Conclusions:
- ART treatment numbers continue to expand across Europe.
- Variability in treatment modalities and rising contribution to birth rates highlight ART's societal impact.
- Data collection methods and completeness vary, requiring cautious interpretation of results.

