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GeodesicSlicer: a Slicer Toolbox for Targeting Brain Stimulation.

F Briend1, E Leroux2, C Nathou2,3

  • 1Normandie Univ, UNICAEN, ISTS EA 7466, GIP CYCERON, F-14000, Caen, France. briend@cyceron.fr.

Neuroinformatics
|March 4, 2020
PubMed
Summary

GeodesicSlicer offers a free, open-source toolkit for NonInvasive Brain Stimulation (NIBS) research, addressing limitations of expensive proprietary software. This customizable tool aids in precise target determination for therapies like repetitive Transcranial Magnetic Stimulation (rTMS).

Keywords:
3D slicerCorrection factorEEGNIBSTarget determinationrTMS

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Area of Science:

  • Neuroscience
  • Medical Imaging
  • Biomedical Engineering

Background:

  • NonInvasive Brain Stimulation (NIBS) shows therapeutic potential but lacks accessible, affordable neuronavigation tools for target determination.
  • Existing neuronavigation software for NIBS is often expensive or proprietary, limiting research accessibility.
  • Accurate targeting is crucial for effective and safe NIBS therapies, including repetitive Transcranial Magnetic Stimulation (rTMS).

Observation:

  • A new open-source software toolkit, GeodesicSlicer, has been developed as an extension for the 3D Slicer platform.
  • GeodesicSlicer integrates functional or anatomical images for precise cortical stimulation target identification.
  • The toolkit includes modules for electrode positioning based on the 10-20 electroencephalogram system and rTMS dose correction.

Findings:

  • GeodesicSlicer provides a customizable, free, and open-source solution for NIBS therapy research.
  • It enables reproducible and inexpensive positioning of Transcranial Magnetic Stimulation (TMS) coils using a triangulation-based MRI-guided method.
  • The software offers a user-friendly graphical interface with tested algorithms for NIBS target determination.

Implications:

  • GeodesicSlicer democratizes NIBS research by offering a viable alternative to costly neuronavigation systems.
  • This toolkit can accelerate research and clinical application of NIBS therapies in laboratories with limited resources.
  • The open-source nature facilitates collaboration and further development in the field of brain stimulation.