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Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility
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Microglia in Alzheimer's disease: Local heroes!
Nàdia Villacampa1, Michael T Heneka1,2,3
1German Center for Neurodegenerative Disease, Bonn, Germany.
The Journal of Experimental Medicine
|March 4, 2020
Abstract:
In this issue of JEM, Reed-Geaghan et al. (https://doi.org/10.1084/jem.20191374) address the long-standing question about the primary source of myeloid cells located at β-amyloid deposits. Using genetic labeling experiments, the authors identify resident microglia as the only myeloid cells present at β-amyloid deposits.
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