Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

31.7K
Overview
31.7K
Antibody Structure01:10

Antibody Structure

65.1K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
65.1K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.3K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal Mechanism of Antitumoral Ni(II) Thiosemicarbazones: Deep Mechanistic Understanding of ROS Dynamics, Albumin-Mediated Delivery, and DNA Targeting.

ACS omega·2026
Same author

Genotoxic Damage and microRNA Dysregulation in Firefighters: An Integrated Biomonitoring Case Study.

Journal of xenobiotics·2026
Same author

Switching to a Low Global Warming Potential Propellant in a Pressurized Metered-Dose Inhaler Does Not Affect the Pharmacokinetics of Combined Beclometasone Dipropionate/Formoterol Fumarate.

Clinical therapeutics·2026
Same author

Atrial fibrillation and coexisting cerebral amyloid angiopathy: safety and efficacy of transcatheter left atrial appendage occlusion.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Alpha-1 Antitrypsin Replacement Improves Walking Capacity in Subjects With Severe Deficiency.

Respiratory care·2026
Same author

A metabolic trade-off between malignant plasma cells and mesenchymal stromal cells sustains multiple myeloma growth.

Blood neoplasia·2026
Same journal

Background Music in elderly nursing home: a feasibility explorative study.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Needle stick injuries among nurses in Italy: a review.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Self-compassion and secondary traumatization: results of an observational study carried out in Covid hospital ordinary units].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Remote functional evaluation after reconstruction of the anterior cruciate ligament in amateur sportsmen with sedentary work].

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

Communicating bad news: attitudes and modes of communication of the health professions.

Giornale italiano di medicina del lavoro ed ergonomia·2023
Same journal

[Mortality study in a cohort of entertainment workers].

Giornale italiano di medicina del lavoro ed ergonomia·2023
See all related articles

Related Experiment Video

Updated: Dec 27, 2025

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.1K

[Laboratory animal allergy.]

Massimo Corradi1, Luisella Selis1, Giovanna Pelà1

  • 1Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma, Via Gramsci 14, 43126 Parma.

Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia
|March 4, 2020
PubMed
Summary
This summary is machine-generated.

Laboratory animal allergy (LAA) affects facility personnel due to allergens in animal waste and saliva. Diagnosis varies, impacting accurate prevalence and incidence reporting in occupational health studies.

Keywords:
allergyasthmalaboratory animals

More Related Videos

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.7K
Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

19.9K

Related Experiment Videos

Last Updated: Dec 27, 2025

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

41.1K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.7K
Measuring Local Anaphylaxis in Mice
07:49

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

19.9K

Area of Science:

  • Occupational Health
  • Immunology
  • Allergology

Background:

  • Laboratory animal allergy (LAA) results from hypersensitivity to animal allergens.
  • Personnel in laboratory animal facilities are at risk, including technicians, researchers, and administrative staff.

Purpose of the Study:

  • To summarize the etiology, risk factors, and diagnostic challenges of LAA.

Main Methods:

  • Review of epidemiological studies on LAA prevalence and incidence.
  • Analysis of diagnostic criteria variability.

Main Results:

  • Reported LAA prevalence ranges from 6% to 44%.
  • Reported LAA incidence ranges from 9% to 30%.
  • Wide variation in data is attributed to non-uniform diagnostic methods.

Conclusions:

  • Standardized diagnostic criteria are needed for accurate LAA assessment.
  • Understanding LAA prevalence is crucial for occupational safety in research settings.