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In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
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Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
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Identifying subgroups: Part 1: Patterns among cross-sectional data.

Christopher S Lee1, Kenneth M Faulkner1, Jessica H Thompson1

  • 1Boston College William F. Connell School of Nursing, USA.

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|March 5, 2020
PubMed
Summary
This summary is machine-generated.

Latent class mixture modeling helps identify subgroups in nursing and allied health research. This person-centered approach explores sample heterogeneity, offering valuable insights for researchers.

Keywords:
Latent class mixture modelinglatent modelsstructural equation modelingsubgroup analysis

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Area of Science:

  • Nursing Research
  • Allied Health Sciences
  • Quantitative Psychology

Background:

  • Non-experimental research designs are prevalent in nursing and allied health.
  • Identifying distinct subgroups within study samples is crucial for understanding heterogeneity.
  • Existing methods for subgroup identification may not fully capture complex patterns.

Purpose of the Study:

  • To introduce latent class mixture modeling (LCMM) as a powerful analytic strategy.
  • To provide a worked example of LCMM application in nursing and allied health research.
  • To enhance researchers' understanding of LCMM's capabilities for exploring sample heterogeneity.

Main Methods:

  • Latent class mixture modeling (LCMM) was employed as the primary analytic technique.
  • A worked example demonstrating the application of LCMM is presented.
  • The focus is on a person-centered approach to subgroup identification.

Main Results:

  • LCMM effectively identifies distinct subgroups within complex samples.
  • The analysis revealed underlying heterogeneity not apparent with traditional methods.
  • The worked example illustrates the practical implementation and interpretation of LCMM.

Conclusions:

  • Latent class mixture modeling is a versatile tool for subgroup analysis in health research.
  • This method allows for a nuanced exploration of heterogeneity in non-experimental studies.
  • Researchers are encouraged to utilize LCMM for deeper insights into their sample characteristics.