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Updated: Dec 27, 2025

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
Published on: February 9, 2019
Optical coherence tomography angiography (OCTA) applications in ocular oncology
Masood Naseripour1, Khalil Ghasemi Falavarjani1, Reza Mirshahi1
1Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Optical coherence tomography angiography (OCTA) offers new ways to view ocular vascular systems. While OCTA shows promise in ocular oncology, current limitations require further technological advancement for broader clinical application.
Area of Science:
- Ophthalmology
- Medical Imaging
- Oncology
Background:
- Optical coherence tomography angiography (OCTA) is a key imaging modality for visualizing ocular vasculature.
- Its application in ocular oncology has been explored for lesion differentiation and complication assessment.
Purpose of the Study:
- To review the current applications of OCTA in ocular oncology.
- To identify limitations of OCTA in this field.
- To discuss the future potential of OCTA in ocular oncology.
Main Methods:
- Review of current literature on OCTA in ocular oncology.
- Analysis of OCTA's capabilities and limitations in visualizing ocular tumors and related conditions.
Main Results:
- OCTA aids in differentiating benign and malignant ocular lesions.
- It assists in evaluating post-treatment complications like radiation retinopathy.
- Current OCTA technology faces artifacts and limitations, especially with elevated tumors.
Conclusions:
- OCTA is a valuable tool in ocular oncology, despite current limitations.
- Advancements in OCTA systems and image acquisition are expected to enhance its utility.
- Future developments hold significant potential for OCTA's role in managing ocular tumors.
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