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Microscopic polyangiitis: an incidental finding in a patient with stroke
Abubakar Tauseef1, Muhammad Sohaib Asghar1, Mariam Amir1
1Internal Medicine, Dow University Hospital, DUHS, Karachi, Pakistan.
Summary
Microscopic polyangiitis (MPA), a small vessel vasculitis, rarely presents as an isolated stroke in young adults. This case highlights MPA
Area of Science:
- Rheumatology
- Neurology
- Pathology
Background:
- Microscopic polyangiitis (MPA) is a small-vessel vasculitis associated with anti-neutrophilic cytoplasmic antibodies.
- Typical MPA symptoms include fever, rash, and peripheral neuropathy.
Observation:
- A 39-year-old female presented with stroke symptoms, a rare initial manifestation.
- MPA was diagnosed incidentally in this patient.
Findings:
- Cerebral infarction as an isolated finding is exceptionally rare in MPA.
- Neurological involvement in MPA most commonly manifests as peripheral neuropathy.
Implications:
- This case underscores the importance of considering MPA in young stroke patients.
- Highlights the diverse and rare neurological presentations of MPA.
- Emphasizes the need for early diagnosis and management of vasculitis.

