Fibroepithelial Polyp Originating from the Nasal Septum
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Published on: March 10, 2016
Marko Stoiljkov1, Aleksandar Perić2
1Unit of Ear Nose Throat, General Hospital Bar, Bar, Montenegro.
Abstract:
Fibroepithelial polyp (FEP) is a rare clinical condition of mesodermal origin, covered usually by squamous epithelium, originating most frequently from the skin, genitourinary and lower respiratory tract. Upper airway FEP is a rare lesion found usually in the pharynx and larynx. Only three cases of FEP arising from the nasal mucosa were reported in the world literature, all from the inferior nasal turbinate. In this paper, we describe the first case in the literature of a FEP originating from the nasal septum in a patient suffering from perennial allergic rhinitis. In addition, we discussed the etiology, pathogenesis, histopathological and clinical characteristics of FEPs.
Insights
This study reports the first nasal septum fibroepithelial polyp (FEP), a rare mesodermal tumor, in a patient with allergic rhinitis. It details the characteristics and discusses the origins of this uncommon upper airway lesion.
Area of Science:
- Otorhinolaryngology
- Pathology
- Dermatology
Background:
- Fibroepithelial polyp (FEP) is a rare mesodermal tumor, typically affecting the skin, genitourinary, and lower respiratory tracts.
- Upper airway FEPs are uncommon, primarily occurring in the pharynx and larynx.
- Previous reports of nasal mucosal FEPs (3 cases) originated solely from the inferior nasal turbinate.
Observation:
- This paper documents the first reported case of a fibroepithelial polyp originating from the nasal septum.
- The patient presented with perennial allergic rhinitis.
- The lesion's etiology, pathogenesis, histopathology, and clinical presentation were analyzed.
Findings:
- A novel case of fibroepithelial polyp (FEP) arising from the nasal septum is described.
- This represents the fourth reported instance of FEP originating in the nasal mucosa and the first from the nasal septum.
- The case highlights a potential association between FEPs and allergic rhinitis.
Implications:
- This finding expands the known anatomical distribution of fibroepithelial polyps within the nasal cavity.
- It underscores the importance of considering FEPs in the differential diagnosis of nasal septal masses, particularly in patients with allergic conditions.
- Further research into the pathogenesis and potential triggers of nasal FEPs is warranted.
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