Fibroepithelial Polyp Originating from the Nasal Septum

Marko Stoiljkov1, Aleksandar Perić2

  • 1Unit of Ear Nose Throat, General Hospital Bar, Bar, Montenegro.

Insights

This study reports the first nasal septum fibroepithelial polyp (FEP), a rare mesodermal tumor, in a patient with allergic rhinitis. It details the characteristics and discusses the origins of this uncommon upper airway lesion.

Area of Science:

  • Otorhinolaryngology
  • Pathology
  • Dermatology

Background:

  • Fibroepithelial polyp (FEP) is a rare mesodermal tumor, typically affecting the skin, genitourinary, and lower respiratory tracts.
  • Upper airway FEPs are uncommon, primarily occurring in the pharynx and larynx.
  • Previous reports of nasal mucosal FEPs (3 cases) originated solely from the inferior nasal turbinate.

Observation:

  • This paper documents the first reported case of a fibroepithelial polyp originating from the nasal septum.
  • The patient presented with perennial allergic rhinitis.
  • The lesion's etiology, pathogenesis, histopathology, and clinical presentation were analyzed.

Findings:

  • A novel case of fibroepithelial polyp (FEP) arising from the nasal septum is described.
  • This represents the fourth reported instance of FEP originating in the nasal mucosa and the first from the nasal septum.
  • The case highlights a potential association between FEPs and allergic rhinitis.

Implications:

  • This finding expands the known anatomical distribution of fibroepithelial polyps within the nasal cavity.
  • It underscores the importance of considering FEPs in the differential diagnosis of nasal septal masses, particularly in patients with allergic conditions.
  • Further research into the pathogenesis and potential triggers of nasal FEPs is warranted.

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