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Updated: Dec 27, 2025

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
How to interpret right ventricular remodeling in athletes
María Sanz-de la Garza1, Amelia Carro2, Stefano Caselli3
1Cardiovascular Institute, Hospital Clínic, Barcelona, Spain.
Intense athletic training can cause significant right ventricular (RV) remodeling in athletes. Differentiating physiological RV changes from arrhythmogenic cardiomyopathy (ACM) is crucial for preventing sudden cardiac death.
Area of Science:
- Cardiology
- Sports Medicine
- Exercise Physiology
Background:
- Long-term athletic training induces adaptive cardiac remodeling, known as "athlete's heart."
- The right ventricle (RV) may experience disproportionate stress during intense exercise, potentially leading to significant remodeling.
- Distinguishing physiological RV changes from pathological conditions like arrhythmogenic cardiomyopathy (ACM) is critical.
Purpose of the Study:
- To outline the physiological adaptations of the RV to acute exercise and chronic training.
- To provide guidance on differentiating physiological RV remodeling from cardiomyopathy phenotypes.
- To highlight the importance of distinguishing between normal training adaptations and pathological RV conditions in athletes.
Main Methods:
- Review of physiological responses to acute exercise.
- Analysis of structural and functional changes in the RV due to athletic training.
- Discussion of clinical criteria for differentiating physiological vs. pathological RV remodeling.
Main Results:
- Endurance athletes can exhibit marked RV remodeling due to prolonged exercise-induced stress.
- High-intensity training may accelerate ACM progression and worsen prognosis.
- Specific criteria are needed to differentiate adaptive RV changes from disease.
Conclusions:
- Physiological RV remodeling in athletes is distinct from pathological changes seen in ACM.
- Accurate differentiation is essential for risk stratification and management of sudden cardiac death in athletes.
- Understanding RV adaptations to exercise is key to preventing misdiagnosis of underlying cardiac conditions.
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