Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ethylene glycol intoxication requires a multidisciplinary approach].

Noah Tafer1, Sophie de Seigneux2, Patrick Saudan2

  • 1Service de médecine interne générale, Département de médecine, HUG, 1211 Genève 14.

Revue Medicale Suisse
|March 5, 2020
PubMed
Summary

Ethylene glycol ingestion, though from common antifreeze, can be fatal. Prompt recognition of its severe metabolic complications and multidisciplinary treatment are crucial for patient survival.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasma oxytocin, early predictor of transient postoperative arginine vasopressin deficiency.

The Journal of clinical endocrinology and metabolism·2026
Same author

Renal gluconeogenesis: a key metabolic hub in health and kidney disease.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Assessing kidney fibrosis via multiparametric MRI in native kidney and allografts.

Clinical kidney journal·2026
Same author

Top ten tips to manage patients after acute kidney injury.

Clinical kidney journal·2026
Same author

Characterization of residual kidney function in chronic hemodialysis patients using plasma metabolomics.

Scientific reports·2026
Same author

Revue medicale suisse·2026

Area of Science:

  • Toxicology
  • Internal Medicine
  • Nephrology

Background:

  • Ethylene glycol is a common industrial chemical found in antifreeze.
  • Ingestion can lead to severe, potentially irreversible health consequences, including death.
  • Its widespread availability necessitates awareness among healthcare professionals.

Purpose of the Study:

  • To review the clinical manifestations and metabolic complications of ethylene glycol intoxication.
  • To emphasize the importance of early recognition and diagnosis.
  • To highlight the critical role of multidisciplinary management in treatment.

Main Methods:

  • Literature review of ethylene glycol poisoning cases and treatment strategies.
  • Analysis of clinical presentations and biochemical alterations.

Related Experiment Videos

  • Discussion of therapeutic interventions and supportive care.

    • Main Results:

    • Ethylene glycol poisoning presents with a triad of metabolic acidosis, renal failure, and neurological depression.
    • Delayed diagnosis is associated with worse outcomes.
    • Effective treatment relies on prompt supportive care, fomepizole or ethanol administration, and potentially hemodialysis.

    Conclusions:

    • Early identification of ethylene glycol intoxication is vital for effective management.
    • A multidisciplinary approach involving nephrologists and intensivists is essential.
    • Rapid and appropriate treatment significantly improves patient prognosis.