A 66 Year Old Woman with Recurrent Stroke.
G Abbas Kharal1, P N Sylaja2, Aneesh B Singhal1
1Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Neurology India
|March 5, 2020
Summary
Recurrent strokes can stem from various causes. Prompt diagnosis of inflammatory conditions is crucial for effective treatment and preventing further strokes.
Area of Science:
- Neurology
- Immunology
Background:
- Recurrent strokes present a complex diagnostic challenge, often requiring a broad differential diagnosis.
- Clinical presentation disproportionate to imaging findings necessitates considering inflammatory etiologies.
Observation:
- A 66-year-old woman experienced recurrent strokes with neurological deficits and mental status changes.
- Cerebrospinal fluid analysis revealed an inflammatory profile, suggesting an underlying inflammatory cause.
Findings:
- The patient's recurrent strokes were attributed to an undiagnosed inflammatory condition.
- Initiation of targeted anti-inflammatory therapy led to a complete cessation of stroke events.
Implications:
- This case highlights the importance of considering inflammatory causes in patients with recurrent strokes, especially when clinical and imaging findings are discordant.
- A systematic diagnostic approach integrating clinical, imaging, and laboratory data is essential for identifying and managing inflammatory stroke.
- Early diagnosis and treatment of inflammatory stroke can significantly improve patient outcomes and prevent long-term disability.


