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Updated: Dec 27, 2025

BioMEMS: Forging New Collaborations Between Biologists and Engineers
Published on: November 1, 2007
Micro-/Nanomotors toward Biomedical Applications: The Recent Progress in Biocompatibility
Juanfeng Ou1,2, Kun Liu2, Jiamiao Jiang2
1School of Materials Science and Engineering, Sun Yat-Sen University, Guangzhou, 510275, China.
Artificial micro-/nanomotors offer exciting biomedical potential but require rigorous biocompatibility assessments for clinical translation. This review highlights progress in ensuring these tiny machines are safe for medical use.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Materials Science
Background:
- Artificial micro-/nanomotors mimic natural motors, converting energy into motion for various tasks.
- These devices show significant promise in biomedical applications.
- Current clinical translation is limited due to biocompatibility concerns.
Purpose of the Study:
- To review recent advancements in the biocompatibility of micro-/nanomotors.
- To focus on the biomedical applications of these engineered systems.
- To bridge the gap between nanoengineering, material chemistry, and biomedical fields.
Main Methods:
- Literature review of studies on micro-/nanomotor biocompatibility.
- Analysis of challenges and progress in biomedical applications.
- Synthesis of interdisciplinary research efforts.
Main Results:
- Biocompatibility is a critical factor for the clinical success of micro-/nanomotors.
- Progress has been made in understanding and improving the safety profiles of these devices.
- Several biomedical applications are being explored.
Conclusions:
- Further research and interdisciplinary collaboration are essential for realizing the full potential of micro-/nanomotors in medicine.
- Addressing biocompatibility is key to successful bench-to-bed translation.
- A future platform for real-world applications is anticipated.
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