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Updated: Dec 27, 2025

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
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Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically

Mikhail Krasavin1, Tatiana Sharonova1, Vladimir Sharoyko1

  • 1Saint Petersburg State University, Saint Petersburg, Russian Federation.

Journal of Enzyme Inhibition and Medicinal Chemistry
|March 6, 2020
PubMed

Keywords:
Anticancer agentsMichael acceptorscancer cell defence mechanismscarbonic anhydrase inhibitiondual pharmacophoreshypoxiaoxidative stresssynergistic effectthioredoxin reductase inhibitionzinc-binding group

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