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Updated: Dec 27, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Is Proton Beam Radiotherapy Worthwhile in the Management of Angiosarcoma of the Scalp?
Viviana Vitolo1, Amelia Barcellini2, Alfredo Mirandola1
1National Center of Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy.
Abstract:
In inoperable patients, the management of angiosarcoma of the scalp is challenging. Due to intrinsic, dosimetric and radiobiological properties, proton beam radiotherapy may be an effective and safe option to offer to these difficult-to-cure patients. Here, we report a case of angiosarcoma of the scalp treated successfully with proton beam radiotherapy. Angiosarcoma is a rare malignancy concerning around 2% of soft-tissue sarcomas and 5% of cutaneous soft-tissue sarcomas. Cutaneous angiosarcomas can occur in any part of the body, but the head and neck region is a common primary site and the scalp is a frequent site in elderly patients.

