A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.
Electra D Paskett1,2,3,4, Michael L Pennell5, Mack T Ruffin6
1Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio. electra.paskett@osumc.edu.
Cancer Prevention Research (Philadelphia, Pa.)
|March 6, 2020
Summary
Cervical cancer rates are higher in Appalachia due to factors like screening access, smoking, and HPV. Research refined a multi-level model to understand and address these disparities.
Area of Science:
- Public Health
- Epidemiology
- Cancer Research
Background:
- Appalachian region faces disproportionately high cervical cancer incidence and mortality.
- Understanding the root causes of this health disparity is crucial for targeted interventions.
Purpose of the Study:
- To investigate the reasons behind elevated cervical cancer rates in Appalachia.
- To develop and refine a multi-level model explaining these disparities.
Main Methods:
- Initial projects (2003-2008) focused on known risk factors: screening, smoking, and human papillomavirus (HPV) infection.
- Subsequent projects (2011-2017) addressed a comprehensive multi-level model of contributing factors.
- Iterative refinement of the explanatory model based on project outcomes.
Main Results:
- Identified key risk factors including lack of screening, smoking, and HPV prevalence.
- Developed a refined multi-level model detailing factors contributing to cervical cancer disparities.
- Laid groundwork for future implementation science strategies.
Conclusions:
- A multi-level model effectively explains cervical cancer disparities in Appalachia.
- Future research will focus on implementation science to reduce cervical cancer burden.
- Addressing complex, multi-faceted factors is essential for cancer prevention in the region.
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