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Peritoneal dialysis during congenital heart surgery admissions: insights from a large database
Rohit S Loomba1, Enrique G Villarreal2,3, Ronald A Bronicki2
1Cardiology, Pediatrics, Advocate Children's Hospital, Oak Lawn, IL, USA.
Insights
Peritoneal dialysis in children after congenital heart surgery is linked to lower hospitalization costs but higher mortality. Further research is needed to balance these risks and benefits.
Area of Science:
- Pediatric Cardiology
- Pediatric Critical Care
- Renal Replacement Therapy
Background:
- Fluid overload management post-congenital heart surgery traditionally relies on diuretics, fluid restriction, and dialysis.
- Limited data exists on the specific impact of peritoneal dialysis in this pediatric population.
Purpose of the Study:
- To investigate the association between peritoneal dialysis and clinical outcomes in children undergoing congenital heart surgery.
- To identify factors influencing the use of peritoneal dialysis in this patient group.
Main Methods:
- Retrospective analysis of the Kids' Inpatient Database (1997-2012).
- Inclusion of patients under 18 years old who underwent congenital heart surgery.
- Logistic regression used to identify factors associated with peritoneal dialysis utilization.
Main Results:
- 181 (0.4%) of 46,176 admissions utilized peritoneal dialysis.
- Peritoneal dialysis was associated with a younger mean age (7.6 months) compared to non-dialysis patients (39.6 months).
- Peritoneal dialysis independently correlated with a significant decrease in hospitalization costs (-$57,500) but a significant increase in mortality (OR 1.5).
Conclusions:
- Peritoneal dialysis is utilized in specific pediatric subsets following congenital heart surgery.
- While associated with reduced hospitalization costs, peritoneal dialysis independently increases mortality risk.
- Further investigation is required to elucidate the precise risks and benefits of peritoneal dialysis in children with congenital heart disease.
Background:
The management of fluid overload after congenital heart surgery has been limited to diuretics, fluid restriction, and dialysis. This study was conducted to determine the association between peritoneal dialysis and important clinical outcomes in children undergoing congenital heart surgery.
Methods:
A retrospective review was conducted to identify patients under 18 years of age who underwent congenital heart surgery. The data were obtained over a 16-year period (1997-2012) from the Kids' Inpatient Database. Data analysed consisted of demographics, diagnoses, type of congenital heart surgery, length of stay, cost of hospitalisation, and mortality. Logistic regression was performed to determine factors associated with peritoneal dialysis.
Results:
A total of 46,176 admissions after congenital heart surgery were included in the study. Of those, 181 (0.4%) utilised peritoneal dialysis. The mean age of the peritoneal dialysis group was 7.6 months compared to 39.6 months in those without peritoneal dialysis. The most common CHDs were atrial septal defect (37%), ventricular septal defect (32.6%), and hypoplastic left heart syndrome (18.8%). Univariate analyses demonstrated significantly greater length of stay, cost of admission, and mortality in those with peritoneal dialysis. Regression analyses demonstrated that peritoneal dialysis was independently associated with significant decrease in cost of admission (-$57,500) and significant increase in mortality (odds ratio 1.5).
Conclusions:
Peritoneal dialysis appears to be used in specific patient subsets and is independently associated with decreased cost of stay, although it is associated with increased mortality. Further studies are needed to describe risks and benefit of peritoneal dialysis in this population.
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