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A process for prioritising systematic reviews in tinnitus.

Magdalena Sereda1,2, Don McFerran3, Emma Axon4

  • 1National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Ropewalk House, Nottingham, UK.

International Journal of Audiology
|March 6, 2020
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Summary

A new process prioritizes tinnitus research for systematic reviews, identifying sound therapy, betahistine, and cognitive behavioral therapy as top priorities. This method can guide future reviews for various conditions.

Keywords:
Cochranemanagementprioritysystematic reviewtinnitustreatment

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Area of Science:

  • Evidence-based medicine
  • Systematic review methodology
  • Otolaryngology

Background:

  • Systematic reviews are crucial for evidence-based healthcare decisions.
  • Prioritizing research topics ensures efficient allocation of resources for new or updated reviews.
  • Tinnitus research requires a structured approach to identify the most impactful areas for investigation.

Purpose of the Study:

  • To develop and validate an innovative prioritization process for identifying topics for systematic reviews in tinnitus research.
  • To establish clear criteria for selecting interventions for future systematic reviews.
  • To streamline the identification of high-priority areas within tinnitus research.

Main Methods:

  • A two-stage prioritization process was employed.
  • Stage one involved a scoping review to assess the availability of randomized controlled trial (RCT) evidence.
  • Stage two used pre-defined primary and secondary criteria to rank interventions for systematic review.

Main Results:

  • The process identified three high-priority interventions for systematic review: sound therapy (amplification devices/sound generators), betahistine, and cognitive behavioral therapy.
  • Secondary priorities included Ginkgo biloba, anxiolytics, hypnotics, antiepileptics, and neuromodulation.
  • The methodology was tested using subjective tinnitus and the Cochrane systematic review platform.

Conclusions:

  • A robust process was successfully developed to identify priority areas for Cochrane systematic reviews on tinnitus interventions.
  • The developed prioritization technique is adaptable and can be applied to other clinical conditions and systematic review types.
  • This approach enhances the efficiency and impact of systematic review generation in medical research.