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Updated: Dec 27, 2025

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
Immunotherapy in Multiple Myeloma.
Cinnie Yentia Soekojo1, Melissa Ooi1, Sanjay de Mel1
1Department of Hematology-Oncology, National University Cancer Institute, Singapore, National University Health System, 1E Kent Ridge Road, Singapore 119228, Singapore.
Multiple myeloma, a complex cancer, involves immune dysfunction. Emerging immunotherapies aim to harness the immune system to combat this disease and overcome treatment resistance.
Area of Science:
- Immunology
- Oncology
- Pharmacology
Background:
- Multiple myeloma (MM) is a hematologic malignancy characterized by immune system dysfunction.
- Immune dysfunction significantly impacts MM pathogenesis, disease progression, and resistance to therapies.
Purpose of the Study:
- To review and summarize the latest advancements in immunotherapies for multiple myeloma.
- To highlight the potential of immunomodulatory strategies in the MM treatment landscape.
Main Methods:
- Literature review of recent clinical trials and research publications.
- Analysis of emerging immunotherapy targets and mechanisms in multiple myeloma.
Main Results:
- Several novel immunotherapeutic approaches are showing promise in preclinical and clinical studies.
- Immunotherapies offer new avenues for overcoming drug resistance and improving patient outcomes in MM.
Conclusions:
- Immunotherapy represents a rapidly evolving and promising frontier in multiple myeloma treatment.
- Targeting the immune system holds significant potential for modifying the disease course and enhancing therapeutic efficacy in MM.
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Published on: January 7, 2019
10:04Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
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