Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Thyroid Gland

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

Synthesis and Regulation of Thyroid Hormones

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...

The Parathyroid Glands

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...

Functions of Thyroid Hormones

Functions of Thyroid Hormones

The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...

Primary Lymphoid Organs

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

Lymphoid Cells and Tissues

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dietary B vitamin intake and risk of ulcerative colitis: a case-control study.

European journal of gastroenterology & hepatology·2026

Same author

Case-control study of IL23R rs76418789 polymorphism, smoking, and ulcerative colitis in Japan.

Cytokine·2024

Same author

Coffee and caffeine intake reduces risk of ulcerative colitis: a case-control study in Japan.

Journal of gastroenterology and hepatology·2023

Same author

International comparison of cross-disciplinary integration in industry 4.0: A co-authorship analysis using academic literature databases.

PloS one·2022

Same author

IL12B rs6887695 polymorphism and interaction with alcohol intake in the risk of ulcerative colitis in Japan.

Cytokine·2022

Same author

Active and passive smoking and risk of ulcerative colitis: A case-control study in Japan.

Journal of gastroenterology and hepatology·2021

Search research articles

Related Experiment Video

Updated: Dec 27, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

Ectopic thymic tissue in the thyroid gland.

Yuji Mizukami¹, Akitaka Nanomura¹, Takatoshi Michigishi²

¹Pathology Section, Kanazawa University Hospital, Kanazawa, Japan.

Endocrine Pathology

|March 7, 2020

Summary

This summary is machine-generated.

A unique case of ectopic thymic tissue within the thyroid gland was found in a woman with Graves

Keywords:

Endocr Pathol Endocrine Pathology Volume Parathyroid Tissue Thymoma Thyroid Gland

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

An Ex vivo Culture System to Study Thyroid Development

An Ex vivo Culture System to Study Thyroid Development

Published on: June 6, 2014

Related Experiment Videos

Last Updated: Dec 27, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

An Ex vivo Culture System to Study Thyroid Development

An Ex vivo Culture System to Study Thyroid Development

Published on: June 6, 2014

Area of Science:

Endocrinology
Pathology
Surgical Anatomy

Background:

Graves' disease is an autoimmune disorder affecting the thyroid gland.
Ectopic thymic tissue is rare and its presence within the thyroid is unusual.
Thyroidectomy is a treatment option for medically refractory Graves' disease.

Purpose of the Study:

To report a unique case of ectopic thymic tissue found within the thyroid gland.
To discuss the potential histogenesis of this ectopic thymic tissue.

Main Methods:

Histopathological examination of a thyroidectomy specimen.
Surgical removal of the thyroid gland due to failed medical therapy for Graves' disease.

Main Results:

A continuous track of thymic tissue was identified extending from the thyroid's center to its capsule.
The thymic tissue was located along an interlobular septum within the thyroid gland.

Conclusions:

The presence of ectopic thymic tissue within the thyroid gland, as observed in this case, is a unique finding.
Further discussion on the histogenesis of ectopic thymic tissue in this anatomical location is warranted.